Updated Sep 20, 2015 at 12:53p ET
LeSean McCoy has been cleared to play for the Buffalo Bills after aggravating his injured left hamstring.
The dual-threat running back was in the lineup Sunday at home against the New England Patriots.
Cleveland Browns wide receiver Dwayne Bowe has done enough to overcome his hamstring injury, giving Johnny Manziel a target against the Tennessee Titans. Running back C.J. Spiller was also to make his debut for a new team, overcoming a knee injury well enough to suit up for the New Orleans Saints at home against Tampa Bay.
Here's a look at who is on the inactive list for the 1 p.m. EDT games:
HOUSTON AT CAROLINA
Texans: RB Arian Foster, T Duane Brown, S Lonnie Ballentine, ILB Mike Mohamed, OG Xavier Su'a-Filo, WR Jaelen Strong, OT Oday Aboushi.
Panthers: LB Luke Kuechly, DT Star Lotulelei, RB Cameron Artis-Payne, OT Daryl Williams, S Dean Marlowe, FB Richie Brockel, RB Brandon Wegher.
SAN FRANCISCO AT PITTSBURGH
Steelers: QB Landry Jones, WR Sammie Coates, CB Cortez Allen, OG Chris Hubbard, TE Jesse James, DE LT Walton, DE Caushaud Lyons.
49ers: WR Bruce Ellington, RB Reggie Bush, CB Shareece Wright, OG Brandon Thomas, NT Mike Purcell, C Nick Easton, LB Corey Lemonier.
TAMPA BAY AT NEW ORLEANS
Bucs: QB Ryan Griffin, CB Mike Jenkins, RB Mike James, S Major Wright, OL Jeremiah Warren, OL Matthew Masifillo, DT T.J. Fatinikun.
Saints: QB Garret Grayson, CB Keenan Lewis, S Jairus Byrd, LB Dannell Ellerbe, DT Kaleb Eulls, G Mike McGlynn, DE Tavaris Barnes.
DETROIT AT MINNESOTA
Lions: WR T.J. Jones, LB DeAndre Levy, OG Taylor Boggs, OT Corey Robinson, TE Brandon Pettigrew, DT Caraun Reid, DE Devin Taylor.
Vikings: QB Taylor Heinicke, WR Stefon Diggs, LB Edmond Robinson, OT Jeremiah Sirles, TE Chase Ford, DE Danielle Hunter.
ARIZONA AT CHICAGO
Bears: WR Alshon Jeffery, CB Tracy Porter, RB Ka'Deem Carey, LB Jonathan Bostic, C Hroniss Grasu, OT Tayo Fabuluje, DL Ego Ferguson.
Cardinals: QB Matt Barkley, WR Brittan Golden, RB Andre Ellington, LB Shaq Riddick, OT D.J. Humphries, OG Mike Lupati, NT Xavier Williams.
NEW ENGLAND AT BUFFALO
Patriots: RB James White, C Ryan Wendell, CB Justin Coleman, DE Trey Flowers, DT Dominique Easley, S Nate Ebner.
Bills: QB EJ Manuel, LB Tony Steward, WR Marquise Goodwin, TE Chris Gragg, DT Andre Fluellen, DT Stefan Charles.
SAN DIEGO AT CINCINNATI
Chargers: WR Jacoby Jones, RB Donald Brown, S Jahleel Addae, LB Tourek Williams, G Johnnie Troutman, OL D.J. Flucker, NT Ryan Carrethers.
Bengals: WR Greg Little, WR Mario Alford, CB Chris Lewis-Harris, TE C.J. Uzomah, DT Marcus Hardison, DT Brandon Thompson, DE Margus Hunt.
TENNESSEE AT CLEVELAND
Browns: QB Josh McCown, DB Justin Gilbert, RB Robert Turbin, DB Ibraheim Campbell, LB Scott Solomon, TE E.J. Bibbs.
Titans: QB Charlie Whitehurst, RB Antonio Andrews, CB Jason McCourty, CB Cody Riggs, OG Quinton Spain, TE Delanie Walker.
ATLANTA AT NEW YORK GIANTS
Falcons: WR Devin Hester, LB Brooks Reed, C Gino Gradkowski, WR Justin Hardy, OT Jake Long, DE Malliciah Goodman, OT Bryce Harris.
Giants: WR Victor Cruz, LB Jon Beason, TE Daniel Fells, DT Markus Kuhn, DE Owa Odighizuwa, T Bobby Hart, S Cooper Taylor.
ST. LOUIS AT WASHINGTON
Rams: QB Sean Mannion, RB Todd Gurley, RB Chase Reynolds, OT Darrell Williams, OG Cody Wichmann, WR Brian Quick, DE Eugene Sims.
Redskins: QB Robert Griffin III, WR DeSean Jackson, CB Justin Rogers, LB Martrell Spaight, OG Spencer Long, OT Tom Compton, OG Arie Kouandjio.
—
AP NFL website: www.pro32.ap.org and www.twitter.com/AP-NFL